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HRID712861

反应详情

EQUATION

反应方程式

HRID 712861 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：FC(F)(F)c1ccc(CBr)cc1
HCID123062

1-(Bromomethyl)-4-(trifluoromethyl)benzene

C8H6BrF3

结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3)CC2)cc1
HCID71204684

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(C(F)(F)F)cc3)CC2)cc1
HCID71204731

未命名化合物

PROCEDURE

实验过程

The title compound (D119) (74 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from (R)-methyl 4-(1-(piperidine-2-carboxamido)cyclopropyl)benzoate (D87) (50 mg) and 4-(trifluoromethyl)benzylbromide (0.039 ml). (Na2CO3: 2.5 eq; reaction time: 6 hrs; 60° C.)