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HRID712862

反应详情

EQUATION

反应方程式

HRID 712862 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：Clc1ccc(CBr)cc1
HCID69329

1-(Bromomethyl)-4-chlorobenzene

C7H6BrCl

结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3)CC2)cc1
HCID71204684

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2(NC(=O)[C@H]3CCCCN3Cc3ccc(Cl)cc3)CC2)cc1
HCID71204655

未命名化合物

收率 93.7%

PROCEDURE

实验过程

The title compound (D120) (45 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from (R)-methyl 4-(1-(piperidine-2-carboxamido)cyclopropyl)benzoate (D87) (34 mg) and 4-(Chloro)benzylbromide (35 mg). (Na2CO3: 4 eq; reaction time: 18 hrs; 68° C.)