HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 71186484, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 4-Fluorobenzyl bromide | HCID 68021 | — |
| Reactant | HCID 71186606 | HCID 71186606 | — |
| Product | HCID 71186484 | HCID 71186484 | — |
Reaction Steps
The title compound (D126) (30 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((1S)-1-(6-azaspiro[2.5]octane-5-carboxamido)ethyl)benzoate (D91) (60 mg) and 4-Fluorobenzylbromide (0.074 ml). (Na2CO3: 2.5 eq; reaction time: 4 hrs; 60° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-30a8bdae9702440899df0f53f41fae9c |
| Source note | uspto-grants-2015_11 |