HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 71186580, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | HCID 71186341 | HCID 71186341 | — |
| Product | HCID 71186580 | HCID 71186580 | — |
Reaction Steps
The title compound (D130) (19 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((1S)-1-(5-methyl-6-azaspiro[2.5]octane-5-carboxamido)ethyl)benzoate (D92) (16 mg) and 4-(Trifluoromethyl)benzylbromide (0.011 ml). (Na2CO3: 3 eq; reaction time: 18 hrs; 68° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-84bdb0e8d6cd4534b55e4cc7f668a7d2 |
| Source note | uspto-grants-2015_11 |