HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 71204696, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | HCID 117966688 | HCID 117966688 | — |
| Product | HCID 71204696 | HCID 71204696 | — |
Reaction Steps
The title compound (D142) (6.8 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-(1-((3R)-2-azabicyclo[4.1.0]heptane-3-carboxamido)cyclopropyl)benzoate (diastereoisomers mixture) (D101) (17.5 mg) and 4-(trifluoromethyl)-benzylbromide (0.01 ml). (Cs2CO3: 1.5 eq; Reaction time: 20 hrs; RT).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-1f5ccadf34b94284b89af27ec67f3730 |
| Source note | uspto-grants-2015_11 |