HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 71204732, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | HCID 71204700 | HCID 71204700 | — |
| Product | HCID 71204732 | HCID 71204732 | — |
Reaction Steps
The title compound (D143) (10 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((1S)-1-((3R)-2-azabicyclo[4.1.0]heptane-3-carboxamido)ethyl)benzoate (diastereoisomers mixture) (D102) (20 mg) and 4-(trifluoromethyl)-benzylbromide (0.012 ml). (Cs2CO3: 1.5 eq; Reaction time: 20 hrs; RT).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-3bdc5f012f2f4846b18f2114b1ac891f |
| Source note | uspto-grants-2015_11 |