HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(Bromomethyl)-4-(trifluoromethyl)benzene → HCID 71204658, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | HCID 71204727 | HCID 71204727 | — |
| Product | HCID 71204658 | HCID 71204658 | — |
Reaction Steps
The title compounds (D150) (72 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((1S)-1-((3R)-2-azabicyclo[3.1.0]hexane-3-carboxamido)ethyl)benzoate (D107) (48 mg) and 4-(trifluoromethyl)-benzylbromide (0.031 ml) (Na2CO3: 3 eq; Reaction time: 18 hrs; 68° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-c2b7a4916aa543e8be795ed8875061da |
| Source note | uspto-grants-2015_11 |