HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cesium carbonate → HCID 71204730, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | HCID 71204722 | HCID 71204722 | — |
| Product | HCID 71204730 | HCID 71204730 | — |
Reaction Steps
The title compound (D151) (100 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from (R)-methyl 4-(1-(4,4-dimethylpyrrolidine-2-carboxamido)cyclopropyl)benzoate (D108) (70 mg) and 4-(trifluoromethyl)-benzylbromide (0.041 ml). (Cs2CO3: 1.5 eq; reaction time: 20 hrs, RT)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-79e6b314853d4e60a8a833075630b8b8 |
| Source note | uspto-grants-2015_11 |