HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride → HCID 71186314, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | (S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride | HCID 57462942 | — |
| Reactant | HCID 71186362 | HCID 71186362 | — |
| Product | HCID 71186314 | HCID 71186314 | 98.7% |
Reaction Steps
The title compound (D153) (85 mg) was prepared according to the general procedure for amides preparation (Method A) starting from 3-(4-(trifluoromethyl)benzyl)-3-azabicyclo[3.1.0]hexane-2-carboxylic acid (D110) (55 mg) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (43.3 mg). (EDC.HCl: 1.05 eq; reaction time: 18 hrs; RT)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-41bf38f919d84406a74e1504501cf632 |
| Source note | uspto-grants-2015_11 |