HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 71186480, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride | HCID 57462942 | — |
| Reactant | HCID 71186564 | HCID 71186564 | — |
| Product | HCID 71186480 | HCID 71186480 | 35.2% |
Reaction Steps
The title compound (D155) (12 mg) was prepared according to the general procedure for amides preparation (Method C) starting from 2-(4-(trifluoromethyl)benzyl)-2-azabicyclo[2.2.2]octane-3-carboxylic acid (D111) (22.5 mg) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (17 mg). (Reaction time: 2 hrs; 60° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-c51cf5da48594204a1cac39433bf509c |
| Source note | uspto-grants-2015_11 |