HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 71204692, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride | HCID 57462942 | — |
| Reactant | HCID 86731622 | HCID 86731622 | — |
| Product | HCID 71204692 | HCID 71204692 | 73.8% |
Reaction Steps
The title compound (D160) (67.3 mg) was prepared according to the general procedure for amides preparation (Method A) starting from lithium (2R,4S)-4-fluoro-1-(3-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D114) (60 mg) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (43.5 mg). (Reaction time: 18 hrs; RT)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-be6a6344f0b44b7781d47c555bffa9e3 |
| Source note | uspto-grants-2015_11 |