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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712905Generated: October 29, 2026

Lithium hydroxide, monohydrate → HCID 71204737, compound

https://huagongshe.com/reaction/712905

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 71204656HCID 71204656—
ProductHCID 71204737HCID 7120473769.8%

Reaction Steps

The title compound (E14) (42 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from methyl 4-((1S)-1-((2R)-4-fluoro-1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxamido)ethyl)benzoate (D133) (62 mg). (LiOH H2O: 4 eq; reaction time: 5 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-688d40048d864d1e9ec8501cb487d8b4
Source noteuspto-grants-2015_11