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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712907Generated: October 29, 2026

Lithium hydroxide, monohydrate → HCID 71204672, compound

https://huagongshe.com/reaction/712907

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 71204734HCID 71204734—
ProductHCID 71204672HCID 7120467277.2%

Reaction Steps

The title compound (E16) (15 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from methyl 4-((S)-1-((R)-4,4-difluoro-1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxamido)ethyl)benzoate (D135) (20 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-fccf4f738c4340dfbeb5490c0f0da8da
Source noteuspto-grants-2015_11