HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 71204677, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 71204658 | HCID 71204658 | — |
| Product | HCID 71204677 | HCID 71204677 | 88.9% |
Reaction Steps
The title compound (E33) (62 mg) was prepared according to the general procedure for esters hydrolysis (Method C) starting from methyl 4-((1S)-1-((3R)-2-(4-(trifluoromethyl)benzyl)-2-azabicyclo[3.1.0]hexane-3-carboxamido)ethyl)benzoate (single diastereoisomer 1) (D150) (72 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-45a8adeb257148798777e78d9e6e3e2a |
| Source note | uspto-grants-2015_11 |