HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 20613884, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 71227085 | HCID 71227085 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 20613884 | HCID 20613884 | 100.3% |
Reaction Steps
The a solution of 4-(4-benzyloxy-benzoyl)-piperidine-1-carboxylic acid tert-butyl ester (313 mg, 0.79 mmol) in dichloromethane (10 mL) was added TFA (0.61 mL, 7.9 mmol). The reaction was stirred for 3 hours and then the solvent removed under vacuum and placed under high vacuum to afford the title compound (234 mg). LRMS m/z: ES+=295.9 (M+H), retention time 1.18.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181266B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-9d498433286d4e608a3277a54224f9a6 |
| Source note | uspto-grants-2015_11 |