Benzophenone → HCID 58225130, compound

Participants

Reaction Conditions

Reaction Steps

3-bromobenzocylcobutene (1.5 g, 8.2 mmol) was dissolved in 50 ml of THF. The solution was cooled to −78° C. To the solution was added butyl-lithium (3.6 mL, 2.0 M in hexanes, 9.0 mmol). After 45 minutes, benzophenone (1.34 g, 7.4 mmol) was added in one portion. The reaction was allowed to warm to room temperature overnight. After normal work-up, the residue was purified by column using 1:1 dichloromethane and hexanes as solvent. 0.9 g of the desired product was obtained (42% yield).

Provenance & Evidence