HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → HCID 68438823, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2'-C-methyladenosine | HCID 500900 | — |
| Reactant | Ammonia methanol | HCID 21705897 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Catalyst | HCID 178506449 | HCID 178506449 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 68438823 | HCID 68438823 | — |
Reaction Steps
(Synthesis according to the procedure of J. A. Montgomery, Nucleic Acid Chemistry, 1978, Part II, 681-685 starting with 2′-C-methyladenosine.) Step 1: H2O2, AcOH, 80%; Step 2: BnBr, DMAc, Step 3: NaOH, H2O, EtOH, 30%, Step 4: NH3/MeOH, 80° C., 2 days, 60%; Step 5: H2/Pd/C, 3 atm, MeOH, 30% Step 6: NaNO2, AcOH, H2O, 50%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09186369B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-1fa31e07ed4c415d82536001445400de |
| Source note | uspto-grants-2015_11 |