Ammonia → HCID 67026161, compound

HRID 713791Notes

Reaction equation

HRID 713791 reaction equation
[OH:1][N:2]=[C:3]([NH2:10])[C:4]1[CH:9]=[CH:8][CH:7]=[N:6][CH:5]=1.[F:11][C:12]1[C:20]([F:21])=[C:19]([F:22])[CH:18]=[CH:17][C:13]=1[C:14](O)=O.N>>[F:11][C:12]1[C:20]([F:21])=[C:19]([F:22])[CH:18]=[CH:17][C:13]=1[C:14]1[O:1][N:2]=[C:3]([C:4]2[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=2)[N:10]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 3029322,3,4-Trifluorobenzoic acidHCID 308113N-Hydroxynicotinimidamide

Product 1

HCID 67026161HCID 67026161, compound

Procedure

The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and 2,3,4-trifluorobenzoic acid (Aldrich). 1H NMR (300 MHz, CD3OD) δ 7.37-7.48 (m, J=9.3, 9.3, 7.1, 2.4 Hz, 1H), 7.64 (ddd, J=7.9, 5.0, 1.0 Hz, 1H), 8.08-8.18 (m, 1H), 8.56 (dt, J=8.0, 1.9 Hz, 1H), 8.75 (dd, J=5.0, 1.8 Hz, 1H), 9.30 (dd, J=2.0, 0.8 Hz, 1H) ppm; MS (DCl/NH3) m/z 278 (M+H)+.

Sources & evidence

ORD record
ord-c09d324094a54f69ad119d15be2bd3b3
Source dataset
uspto-grants-2015_11
Patent number
US09186407B2

Reaction notes

Loading…