HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 3-(5-(6-Chloropyridin-3-yl)-1,2,4-oxadiazol-3-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
| Reactant | 3-Cyano-N-hydroxy-benzamidine | HCID 57368933 | — |
| Product | 3-(5-(6-Chloropyridin-3-yl)-1,2,4-oxadiazol-3-yl)benzonitrile | HCID 86621258 | — |
Reaction Steps
The title compound was prepared according to the procedure of Example 4B using 3-cyano-N′-hydroxybenzimidamide (Example 4A) and 6-chloronicotinoyl chloride (Aldrich). 1H NMR (300 MHz, DMSO-d6) δ 7.87 (m, 2H), 8.17 (m, 1H), 8.4 (m, 1H), 8.43 (d, J=1.7 Hz, 1H), 8.6 (m, 1H), 9.25 (d, J=1.7 Hz, 1H) ppm; MS (DCl/NH3) m/z 283 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09186407B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-0e67b242b76144d4a7f45e27f2d8be0a |
| Source note | uspto-grants-2015_11 |