化工社化工社 化学情報印刷レポート · 研究参考用
2,4-Dichloro-5-fluoropyrimidine → N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,4-Dichloro-5-fluoropyrimidine | HCID 250705 | — |
| 反応物 | 6-Aminoindole | HCID 256096 | — |
| 生成物 | N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine | HCID 11552202 | — |
反応手順
In like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 6-aminoindole were reacted to yield N2,N4-bis(indol-6-yl)-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 22.39 min.; purity: 85%; MS (m/e): 359 (MH+).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822685B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-c5d6cd33bab749568bda38be0e12e289 |
| 出典メモ | uspto-grants-2014_09 |