HCID 178445789, compound → HCID 178498775, compound

HRID 713949Notes

Reaction equation

HRID 713949 reaction equation
[CH3:1][O:2][C:3]([CH:5]1[CH2:8][N:7]([CH2:9]C2C=C(C(F)(F)F)C3C(=CC=C(O[C@H]4CC[C@H](C(C)(C)C)CC4)C=3)N=2)[CH2:6]1)=[O:4].[C:35]([C@H:39]1[CH2:44][CH2:43][C@H:42]([O:45][C:46]2[CH:55]=[CH:54][C:53]3[C:48](=[CH:49][CH:50]=[C:51](C=O)[CH:52]=3)[N:47]=2)[CH2:41][CH2:40]1)([CH3:38])([CH3:37])[CH3:36]>>[CH3:1][O:2][C:3]([CH:5]1[CH2:8][N:7]([CH2:9][C:51]2[CH:52]=[C:53]3[C:48](=[CH:49][CH:50]=2)[N:47]=[C:46]([O:45][C@H:42]2[CH2:41][CH2:40][C@H:39]([C:35]([CH3:36])([CH3:38])[CH3:37])[CH2:44][CH2:43]2)[CH:55]=[CH:54]3)[CH2:6]1)=[O:4]

Participants

3

Reactant 2

HCID 178445789HCID 178445789, compoundHCID 178498779HCID 178498779, compound

Product 1

HCID 178498775HCID 178498775, compound

Procedure

Synthesized as per 1-[6-(trans-4-tert-Butyl-cyclohexyloxy)-4-trifluoromethyl-quinolin-2-ylmethyl]-azetidine-3-carboxylic acid methyl ester using 2-(trans-4-tert-Butyl-cyclohexyloxy)-quinoline-6-carbaldehyde as starting material. ESI-MS(M+H+): 411.30.

Sources & evidence

ORD record
ord-9a522978645b4c80881dbeece3eadd78
Source dataset
uspto-grants-2015_11
Patent number
US09186367B2

Reaction notes

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