HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanesulfonyl chloride → N-(4-bromo-6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl)ethanesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanesulfonyl chloride | HCID 11667 | — |
| Reactant | 4-Bromo-6,7-dihydro-5H-cyclopenta[C]pyridin-7-amine | HCID 71743893 | — |
| Product | N-(4-bromo-6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl)ethanesulfonamide | HCID 89456129 | 94% |
Reaction Steps
In analogy to the procedure described for the preparation of example 2, (rac)-4-bromo-6,7-dihydro-5H-cyclopenta[c]pyridin-7-amine (intermediate A-4 [C]) and ethanesulfonyl chloride gave the title compound as a grey solid in 94% yield. MS: 304.99 (M+H+, 1 Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187429B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-ea022da9c9034ecaadb61f10116019c6 |
| Source note | uspto-grants-2015_11 |