反应详情

In a flame dried round-bottomed flask equipped with a magnetic stir bar, a suspension of 4-(benzyloxy)-1-(pyrrolidin-1-yl)butan-1-one (284 mg, 1.15 mmol) and Pd/C (10% Pd, 122 mg) in dry MeOH (10 mL) was stirred at rt under a H2 atmospheric pressure until completion of the reaction. The mixture was then filtered, and the filtrate concentrated under reduced pressure to give the title compound as a colorless oil. LC-MS-conditions 08: tR=0.41 min; [M+H]+=158.07.

1. customIn a flame dried round-bottomed flask equipped with a magnetic stir bar
2. customuntil completion of the reaction
3. filtrationThe mixture was then filtered
4. concentrationthe filtrate concentrated under reduced pressure