HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylalanine amide → (2S)-3-Phenylpropane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylalanine amide | HCID 445694 | — |
| Reactant | 2-Aminopentanenitrile | HCID 10171288 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | (2S)-3-Phenylpropane-1,2-diamine | HCID 12699301 | 35% |
Reaction Steps
Following the procedure as described in Preparation 11, making variations as required to replace 2-aminopentanenitrile with L-phenylalanineamide to react with lithium aluminum hydride, (S)-3-phenylpropane-1,2-diamine was obtained as a colorless solid in 35% yield: MS (ES+) m/z 151.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187426B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-34b84eebebbb4076b5083de9d6f058a5 |
| Source note | uspto-grants-2015_11 |