HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-2-phenylacetonitrile → 1-phenylethane-1,2-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-2-phenylacetonitrile | HCID 40838 | — |
| Reactant | 2-Aminopentanenitrile | HCID 10171288 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Product | 1-phenylethane-1,2-diamine | HCID 432011 | 35% |
Reaction Steps
Following the procedure as described in Preparation 11, making variations as required to replace 2-aminopentanenitrile with 2-amino-2-phenylacetonitrile, (Crossley et al., J. Chem., Perkin Trans. 1, (1974), 2327-2330) to react with lithium aluminum hydride, 1-phenylethane-1,2-diamine was obtained as a colorless solid in 35% yield. The crude product was used for the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187426B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-30932204b2554920a155604fb3febdde |
| Source note | uspto-grants-2015_11 |