3-Phenylpropylamine → HCID 67153857, compound

Participants

Reaction Steps

Following the procedure as described in Example 1, making variations as required to replace (4-(trifluoromethyl)phenyl)methanamine with 3-phenylpropan-1-amine to react with 2-benzamidoisonicotinic acid, 2-benzamido-N-(3-phenylpropyl)-isonicotinamide was obtained as a colorless solid in 72% yield: 1H NMR (300 MHz, DMSO-d6) δ 10.97 (s, 1H), 8.82-8.78 (m, 1H), 8.56-8.50 (m, 2H), 8.05-8.03 (m, 2H), 7.64-7.50 (m, 4H), 7.32-7.16 (m, 5H), 3.31-3.27 (m, 2H), 2.67-2.62 (m, 2H), 1.90-1.80 (m, 2H); MS (ES+) m/z 360.5 (M+1).

Provenance & Evidence