Hydrochloric Acid → HCID 66633775, compound

Participants

Reaction Steps

79 mg (0.15 mmol) of tert-butyl (2-{[(3-{[(6-amino-3,5-dicyano-4-phenylpyridin-2-yl)sulfanyl]-methyl}phenyl)carbonyl]amino}ethyl)carbamate Example 57A were initially charged in 1 ml of dioxane. After addition of 21.6 mg (0.6 mmol) of 4 N hydrochloric acid in dioxane, the mixture was stirred at RT overnight. The reaction mixture was evaporated. The residue was purified by preparative HPLC (Chromasil, water/acetonitrile).

Provenance & Evidence