HCID 58774160, compound → HCID 71254978, compound

Participants

Reaction Steps

To a suspension of 10% palladium on carbon (5 mg, 10 mol %) in 5 mL ethanol which had been stirred vigorously under 1 atmosphere of hydrogen for 10 minutes then cooled with an ice/methanol bath was added a solution of 2-(4-Allyloxy-3-hydroxy-phenyl)-chroman-3,5,7-triol (50 mg) in 2 mL ethanol. The ice bath was removed and the reaction was stirred for 3 h under 1 atmosphere of hydrogen. The mixture was passed through a 0.22 micron nylon syringe filter and concentrated to a foam which was dissolved in acetonitrile/water, frozen, and lyophilized give 2-(3-Hydroxy-4-propoxy-phenyl)-chroman-3,5,7-triol as a white powder.

Provenance & Evidence