反应详情

To a solution of 3-methoxybenzenethiol (5 g, 35.66 mmol) and TEA (7.45 ml, 53.49 mmol) in DCM (60 ml) was added Ac2O (4 g, 39.23 mmol) at room temperature and stirred for 3 hours. The reaction mixture was washed with 1 N HCl (50 ml×2), water (50 ml×2) and brine (50 ml), dried with anhydrous sodium sulfate, filtered and concentrated to afford product as a yellow solid (6.5 g, 100%). MS (ESI): m/z 183.1 [M+1]+.

1. washThe reaction mixture was washed with 1 N HCl (50 ml×2), water (50 ml×2) and brine (50 ml)
2. dry with materialdried with anhydrous sodium sulfate
3. filtrationfiltered
4. concentrationconcentrated