HCID 86694554, compound → HCID 86694555, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:9][C:10]2[C:19]3[C:14](=[CH:15][C:16](F)=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=3)[N:13]=[CH:12][C:11]=2[C:24]#[N:25])[CH:5]=[CH:6][C:7]=1[F:8].[OH:26][C:27]1[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:9][C:10]2[C:19]3[C:14](=[CH:15][C:16]([O:26][C:27]4[CH:32]=[CH:31][N:30]=[CH:29][CH:28]=4)=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=3)[N:13]=[CH:12][C:11]=2[C:24]#[N:25])[CH:5]=[CH:6][C:7]=1[F:8]Participants
3
Procedure
The compound was prepared according to the process of Preparation 2 and with 4-(3-chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinoline-3-carbonitrile and 4-hydroxypyridine as starting materials.
Workup
- customThe compound was prepared
Sources & evidence
- ORD record
- ord-3ae960a487c64e1794dde82864207302
- Source dataset
- uspto-grants-2015_11
- Patent number
- US09187458B2
Reaction notes
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