Carbon tetrabromide → HCID 67396310, compound

Participants

Reaction Steps

177 mg (0.60 mmol) of the compound from Example 115A and 187 mg (0.71 mmol) of triphenyl-phosphine were dissolved in 4 ml of THF, and 237 mg (0.71 mmol) of carbon tetrabromide were added at RT. The mixture was then stirred at RT for 16 h. For work-up, the mixture was filtered through 20 g of kieselguhr and the filtrate was concentrated under reduced pressure. The residue was purified chromatographically [Method 19]. This gave, in a purity of 79%, 129 mg (60% of theory) of the target compound, which were immediately reacted further.

Provenance & Evidence