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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 714694Generated: October 28, 2026

5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one → HCID 86690924, compound

https://huagongshe.com/reaction/714694

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-oneHCID 59536836—
ReactantHCID 67411525HCID 67411525—
ProductHCID 86690924HCID 86690924—

Reaction Steps

40 mg (0.13 mmol) of the compound from Example 5A were reacted with 46 mg (0.13 mmol) of the compound from Example 92A analogously to the preparation of the compound in Example 77. This gave 58 mg (76% of theory) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187466B2
Source datasetuspto-grants-2015_11
ORD IDord-ebe86ba45b3341f09351fb82e37e2873
Source noteuspto-grants-2015_11