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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 714702Generated: October 29, 2026

5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one → HCID 69940091, compound

https://huagongshe.com/reaction/714702

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-oneHCID 59536836—
ReactantHCID 67396301HCID 67396301—
ProductHCID 69940091HCID 69940091—

Reaction Steps

Analogously to the preparation of the compound in Example 89, 261 mg (0.85 mmol) of the compound from Example 5A and 240 mg (0.85 mmol) of the compound from Example 65A were reacted with one another. This gave 249 mg (54% of theory) of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187466B2
Source datasetuspto-grants-2015_11
ORD IDord-3337de7c9fbb45b1938c88ee9d7e8914
Source noteuspto-grants-2015_11