Cesium carbonate → HCID 86690930, compound

Participants

Reaction Conditions

Reaction Steps

37 mg (0.12 mmol) of the compound from Example 82A were dissolved in 2 ml of acetonitrile, and 39 mg (0.13 mmol) of the compound from Example 5A and 57 mg (0.18 mmol) of cesium carbonate were added. The mixture was stirred at 60° C. for 2.5 h. After cooling to RT, the solid was filtered off and rinsed with a little acetonitrile. The filtrate was concentrated under reduced pressure and directly purified chromatographically [Method 19]. The product obtained was subjected to a further chromatographic purification on silica gel (mobile phase: cyclohexane/ethyl acetate 4:1, then 3:2). This gave 28 mg (41% of theory) of the target compound.

Provenance & Evidence