Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 714743Generated: October 29, 2026

5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one → HCID 69940401, compound

https://huagongshe.com/reaction/714743

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-oneHCID 59536836—
ReactantHCID 67396291HCID 67396291—
ProductHCID 69940401HCID 69940401—

Reaction Steps

Analogously to the preparation of Example 139, 208 mg (0.68 mmol) of the compound from Example 5A were reacted with 230 mg (0.68 mmol) of the compound from Example 109A. This gave 231 mg (59% of theory) of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187466B2
Source datasetuspto-grants-2015_11
ORD IDord-61e4ccaaff00471586b2da642586c55c
Source noteuspto-grants-2015_11