HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one → HCID 69940339, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one | HCID 59536836 | — |
| Reactant | HCID 67396375 | HCID 67396375 | — |
| Product | HCID 69940339 | HCID 69940339 | — |
Reaction Steps
Analogously to the preparation of Example 139, 248 mg (0.81 mmol) of the compound from Example 5A were reacted with 274 mg (0.81 mmol) of the compound from Example 112A. This gave 271 mg (59% of theory) of the target compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187466B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-07d6ea3a675e4887adf1cc0e7ff390a0 |
| Source note | uspto-grants-2015_11 |