反应详情

To a solution of (1-(4-nitro-1H-pyrazol-1-yl)cyclopropyl)methanol (300 mg) obtained in Step B of Example 128 in ethanol (20 mL) was added palladium-activated carbon ethylene diamine complex (Pd: 8.5-11.5%) (100 mg), and the mixture was stirred at room temperature for 5 hr under hydrogen atmosphere (at normal pressures). The palladium-activated carbon ethylene diamine complex was removed by filtration through Celite, and the solvent was evaporated under reduced pressure to give the title compound (250 mg).

1. customThe palladium-activated carbon ethylene diamine complex was removed by filtration through Celite
2. customthe solvent was evaporated under reduced pressure