HCID 117840323, compound → HCID 117840875, compound

Participants

Reaction Steps

To a solution of N-methyl-4-(4-nitrophenyl)tetrahydro-2H-pyran-4-carboxamide (380 mg) obtained in Step C of Example 151 in ethanol (20 mL) was added 10% palladium-carbon (100 mg), and the mixture was stirred at room temperature for 10 hr under hydrogen atmosphere (at normal pressures). The palladium-carbon was removed by filtration through Celite, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (NH, hexane/ethyl acetate) to give the title compound (330 mg).

Provenance & Evidence