HCID 131734077, compound → HCID 117840935, compound

Participants

Reaction Steps

To a solution of the crude benzyl(6-(1-amino-2-methyl-1-oxopropan-2-yl)pyridin-3-yl)carbamate (880 mg) obtained in Step E of Example 153 in ethanol (30 mL) was added 10% palladium-carbon (90 mg), and the mixture was stirred overnight at room temperature under hydrogen atmosphere (at normal pressures). The palladium-carbon was removed by filtration through Celite, the solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate/methanol) to give the title compound (100 mg).

Provenance & Evidence