HCID 117841056, compound → HCID 117840190, compound

Participants

Reaction Steps

To a solution of tert-butyl 2-cyclopropyl-4-nitrobenzoate (500 mg) obtained in Step B of Example 301 in ethanol (5.0 mL) was added 10% palladium-carbon (100 mg), and the mixture was stirred at room temperature for 3 hr under hydrogen atmosphere (at normal pressures). The palladium-carbon was removed by filtration, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (hexane/ethyl acetate) to give the title compound (300 mg).

Provenance & Evidence