N-(2-(4-nitro-1H-pyrazol-1-yl)ethyl)acetamide → N-[2-(4-amino-1H-pyrazol-1-yl)ethyl]acetamide

Participants

Reaction Steps

To a solution of N-(2-(4-nitro-1H-pyrazol-1-yl)ethyl)acetamide (610 mg) obtained in Step C of Example 348 in ethanol (20 mL) was added 10% palladium-carbon (160 mg), and the mixture was stirred at room temperature for 3 hr under hydrogen atmosphere (at normal pressures). The palladium carbon was removed by filtration through Celite, and the solvent was evaporated under reduced pressure to give the title compound (570 mg).

Provenance & Evidence