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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 714962Generated: October 29, 2026

4-Bromobenzoyl chloride → Ethyl 5-(4-bromophenyl)oxazole-4-carboxylate

https://huagongshe.com/reaction/714962

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromobenzoyl chlorideHCID 68515—
ReactantEthyl 5-(4-methoxyphenyl)-1,3-oxazole-4-carboxylateHCID 2739749—
ProductEthyl 5-(4-bromophenyl)oxazole-4-carboxylateHCID 2758809—

Reaction Steps

Prepared from 4-bromobenzoyl chloride according to the procedure outlined for ethyl 5-(4-methoxyphenyl)oxazole-4-carboxylate in example M-1. 1H NMR (DMSO) δ 1.42 (3H, t), 4.42 (2H, q), 7.61 (2H, d), 7.92 (1H, s), 7.99 (2H, d). LCMS (1) Rt: 2.10 min; m/z (ES+) 268/270 MH+-Et.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187465B2
Source datasetuspto-grants-2015_11
ORD IDord-28ee2b30564d4f5a8bad5390e1a4a803
Source noteuspto-grants-2015_11