HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86681767, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2,6-Dichloropyrazine | HCID 78504 | — |
| Reactant | 1-Methylazetidin-3-ol | HCID 13813927 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86681767 | HCID 86681767 | — |
Reaction Steps
2-chloro-6-((1-methylazetidin-3-yl)oxy)pyrazine (129) was prepared by reacting 1-methylazetidin-3-ol (50 mg, 0.336 mmol, 1 eq) and 2,6-dichloropyrazine (32) (29.2 mg, 0.336 mmol, 1 eq) in DMF (5 mL) and sodium hydride (16.11 mg, 0.671 mmol, 2 eq) under refluxing temperature for 8 hrs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187473B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-099ab519b47a4706942a1f4a7e62a6f6 |
| Source note | uspto-grants-2015_11 |