反应详情

The title compound is prepared in 75% yield (158 mg, colorless oil) from methyl 3-(bromomethyl)-2-chloroisonicotinate (150 mg, 0.57 mmol) and (5-chloro-6-(2,2-difluoroethoxy)pyridin-3-yl)methanamine hydrochloride (147 mg, 0.57 mmol, Amine-12) in a similar manner to Intermediate-2.