HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(bromomethyl)-2-chloropyridine-4-carboxylate → HCID 89875489, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(bromomethyl)-2-chloropyridine-4-carboxylate | HCID 72213786 | — |
| Reactant | HCID 87426614 | HCID 87426614 | — |
| Product | HCID 89875489 | HCID 89875489 | 60% |
Reaction Steps
The title compound is prepared in 60% yield (132 mg, white solid) from methyl 3-(bromomethyl)-2-chloroisonicotinate (150 mg, 0.57 mmol) and (6-(2,2,3,3-tetrafluoropropoxy)pyridin-3-yl)methanamine hydrochloride (156 mg, 0.57 mmol, Amine-14) in a similar manner to Intermediate-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187475B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-acdb742f650a4011b976eb91e4e30f2e |
| Source note | uspto-grants-2015_11 |