HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 87426372, compound → HCID 89873995, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 87426372 | HCID 87426372 | — |
| Reactant | Ethyl 3-(bromomethyl)-2-chloroisonicotinate | HCID 89874240 | — |
| Product | HCID 89873995 | HCID 89873995 | 71% |
Reaction Steps
The title compound is prepared in 71% yield (360 mg, pale yellow solid) from ethyl 3-(bromomethyl)-2-chloroisonicotinate (350 mg, 1.3 mmol, Step-1 of Intermediate-1) and (5-methyl-6-(2,2,3,3-tetrafluoropropoxy)pyridin-3-yl)methanamine (410 mg, 1.3 mmol, Amine-51) in a similar manner to Intermediate-2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187475B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-4903e1f1e9cb4d0faeae38e19e9b1f00 |
| Source note | uspto-grants-2015_11 |