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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 715339Generated: October 30, 2026

HCID 62291629, compound → HCID 89874501, compound

https://huagongshe.com/reaction/715339

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 62291629HCID 62291629—
ReactantEthyl 3-(bromomethyl)-2-chloroisonicotinateHCID 89874240—
ProductHCID 89874501HCID 8987450181%

Reaction Steps

The title compound is prepared in 81% yield (1.01 g, white solid) from ethyl 3-(bromomethyl)-2-chloroisonicotinate (917 mg, 3.29 mmol, Step-1 of Intermediate-1) and (5-chloro-6-(2,2,3,3-tetrafluoropropoxy)pyridin-3-yl)methanamine (800 mg, 2.93 mmol, Amine-87) in a similar manner to Intermediate-2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187475B2
Source datasetuspto-grants-2015_11
ORD IDord-9e55805330274a3c9c84660284b1c450
Source noteuspto-grants-2015_11