化工社化工社 化学情報印刷レポート · 研究参考用
Methanol → Methyl p-aminosalicylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methanol | HCID 887 | — |
| 反応物 | 4-Aminosalicylic Acid | HCID 4649 | — |
| 生成物 | Methyl p-aminosalicylate | HCID 77787 | — |
反応手順
A solution of 4-amino-2-hydroxybenzoic acid (1 g, 6.5 mmol) in MeOH (15 mL) and concentrated sulfonic acid (1 mL) was refluxed overnight. The reaction mixture was quenched with NaHCO3 aqueous solution (60 mL) and EtOAc (60 mL). The organic layer was separated, dried, evaporated to give 3-hydroxy-4-methoxycarbonylaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08822685B2 |
| 出典データセット | uspto-grants-2014_09 |
| ORD ID | ord-aba6bdb960ce41dead32062ee1bf5d05 |
| 出典メモ | uspto-grants-2014_09 |