HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Bromomethylcyclopropane → 2-Chloro-5-(cyclopropylmethoxy)-4-methylpyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Bromomethylcyclopropane | HCID 81503 | — |
| Edukt | 2-Chloro-5-hydroxy-4-methylpyridine | HCID 71299549 | — |
| Produkt | 2-Chloro-5-(cyclopropylmethoxy)-4-methylpyridine | HCID 89874924 | 86% |
Reaktionsschritte
The title compound is prepared in 86% yield (3.57 g, colorless oil) from 6-chloro-4-methylpyridin-3-ol (3.00 g, 20.9 mmol) and (bromomethyl)cyclopropane (3.39 g, 25.1 mmol) in a similar manner to Step-1 of Amine-49.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09187475B2 |
| Quelldatensatz | uspto-grants-2015_11 |
| ORD ID | ord-9f183041bb844e89a1258ac6d9473db8 |
| Quellennotiz | uspto-grants-2015_11 |