(4-Bromophenyl)boronic acid → (3R,3aR,6R,6aR)-6-(5-(4-Bromophenyl)-6-chloro-3-((2-(trimethylsilyl)ethoxy)methyl)-3H-imidazo[4,5-b]pyridin-2-yloxy)hexahydrofuro[3,2-b]furan-3-ol

Participants

Reaction Steps

The title compound is prepared from (3R,3aR,6R,6aR)-6-(6-chloro-5-iodo-3-((2-(trimethylsilyl)ethoxy)methyl)-3H-imidazo[4,5-b]pyridin-2-yloxy)hexahydrofuro[3,2-b]furan-3-ol and 4-bromophenylboronic acid following a procedure analogous to that described for Intermediate 3. LC (method 2): tR=1.24 min; Mass spectrum (ESI+): m/z=582 [M+H]+.

Provenance & Evidence